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David Žihala

Projects

Academic degree, name, surname:

Mgr. David Žihala, Ph.D.

Room, floor, building:

Position:

Research interests and teaching:

Department (Faculty):

Department of Haematooncology (Faculty of Medicine)
Environmental Center (Faculty of Science)
Medical Research Center (Faculty of Medicine)

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No record found.

An expanded phylogenomic analysis of Heterolobosea reveals the deep relationships, non-canonical genetic codes, and cryptic flagellate stages in the group

Tomáš Pánek, Alexander K. Tice, Pia Corre, Pavla Hrubá, David ŽIHALA, Ryoma Kamikawa, Euki Yazaki, Takashi Shiratori, Keitaro Kume, Tetsuo Hashimoto, Ken-Ichiro Ishida, Miluše Hradilová, Jeffrey D. Silberman, Andrew Roger, Yuji Inagaki, Marek Eliáš, Matthew W. Brown, Ivan Cepicka ... other authors

Year: 2025, Molecular Phylogenetics and Evolution

journal article

Deubiquitinase BAP1 is crucial for surface expression of T cell receptor (TCR) complex, T cell-B cell conjugate formation, and T cell activation

Dhwani Radhakrishnan, Jana Kotulová, Lucie Hofmanová, Anjana Anilkumar Sithara, Marcello Turi, David ŽIHALA, Michal Ďurech, Jan VRÁNA, Valeria Uleri, Veronika Niederlova, Stepanek Ondrej, Zuzana Chyra, Tomáš Jelínek, Roman Hájek, Matouš Hrdinka ... other authors

Year: 2025, Journal of Leukocyte Biology

journal article

Real-World Evidence on Prognostic Value of MRD in Multiple Myeloma Using Flow Cytometry

Ludmila MUROŇOVÁ, Ondřej Souček, David ŽIHALA, Tereza Ševčíková, Tereza Popková, Hana Plonkova, Ondřej Venglář, Ludek Pour, Martin Stork, Lucie Rihova, Renata Bezdekova, Jiri Minarik, Vojtěch Látal, Martin Novák, Alexandra Jungova, Tereza Dekojova, Jan Straub, Martin Spacek, Vladimira Rezacova, Vladimír Maisnar, Jakub Radocha, Roman Hájek, Tomáš Jelínek ... other authors

Year: 2025, European Journal of Haematology

journal article

Beyond the marrow: insights from comprehensive next-generation sequencing of extramedullary multiple myeloma tumors

Tomáš Jelínek, David ŽIHALA, Tereza Ševčíková, Anjana Anilkumar Sithara, Veronika Kapustová, Hana Šahinbegović, Ondřej Venglář, Ludmila MUROŇOVÁ, Lucie Broskevičová, Serafim Nenarokov, Daniel Bílek, Tereza Popková, H. Plonkova, Jan VRÁNA, V. Zidlik, P. Hurník, Martin Havel, Matouš Hrdinka, Zuzana Chyra, G. Stracquadanio, Michal Šimíček, Roman Hájek ... other authors

Year: 2024, LEUKEMIA

journal article

Beyond the marrow: insights from comprehensive nextgeneration sequencing of extramedullary multiple myeloma tumors

Tomáš Jelínek, David ŽIHALA, Tereza Ševčíková, Anjana Anilkumar Sithara, Veronika Kapustová, Hana Šahinbegović, Ondřej Venglář, Ludmila MUROŇOVÁ, Lucie Broskevičová, Serafim Nenarokov, Daniel Bílek, Tereza Popková, H. Plonková, Jan VRÁNA, Vladimír Židlík, Pavel Hurník, Martin Havel, Matouš Hrdinka, Zuzana Chyra, G. Stracquadanio, Michal Šimíček, Roman Hájek ... other authors

Year: 2024, Leukemia

journal article

Insight into the mechanism of CD34+ cell mobilisation impairment in multiple myeloma patients treated with anti-CD38 therapy

Ondřej Venglář, Veronika Kapustová, Anjana Anilkumar Sithara, David ŽIHALA, Ludmila MUROŇOVÁ, Tereza Ševčíková, Jan Vrana, Alexander Vdovin, Jakub Radocha, Petra Krhovska, Matouš Hrdinka, Michal Turjap, Tereza Popková, Zuzana Chyra, Lucie Broskevičová, Michal Šimíček, Zdeněk Kořístek, Roman Hájek, Tomáš Jelínek ... other authors

Year: 2024, BRITISH JOURNAL OF HAEMATOLOGY

journal article

Spatial transcriptomics reveals profound subclonal heterogeneity and T-cell dysfunction in extramedullary myeloma

John Mara, Helal Moutaz, Johannes Duell, Greta Mattavelli, Emilia Stanojkovska, Nazia Afrin, Alexander M. Leipold, Maximilian J. Steinhardt, Xiang Zhou, David ŽIHALA, Anjana Anilkumar Sithara, Julia Mersi, Johannes M. Waldschmidt, Christine Riedhammer, Sofie-Katrin Kadel, Marietta Truger, Rudolf A. Werner, Claudia Haferlach, Einsele Hermann, Kai Kretzschmar, Tomáš Jelínek, Andreas Rosenwald, K. Martin Kortuem, Angela Riedel, Leo Rasche ... other authors

Year: 2024, Blood

journal article

More Than 2% of Circulating Tumor Plasma Cells Defines Plasma Cell Leukemia-Like Multiple Myeloma

Tomáš Jelínek, Renata Bezdekova, David ŽIHALA, Tereza Ševčíková, Anjana Anilkumar Sithara, Lenka Pospisilova, Sabina Sevcikova, Petra Polackova, Martin Stork, Zdenka Knechtova, Ondřej Venglář, Veronika Kapustová, Tereza Popková, Ludmila MUROŇOVÁ, Zuzana Chyra, Matouš Hrdinka, Michal Šimíček, Juan-Jose Garces, Noemi Puig, Maria-Teresa Cedena, Artur Jurczyszyn, Jorge J. Castillo, Miroslav Penka, Jakub Radocha, Maria Victoria Mateos, Jesus F. San-Miguel, Bruno Paiva, Ludek Pour, Lucie Rihova, Roman Hájek ... other authors

Year: 2023, JOURNAL OF CLINICAL ONCOLOGY

journal article

Transcriptome Analysis of Diffuse Large B-Cell Lymphoma Cells Inducibly Expressing MyD88 L265P Mutation Identifies Upregulated CD44, LGALS3, NFKBIZ, and BATF as Downstream Targets of Oncogenic NF-κB Signaling

Marcello Turi, Anjana Anilkumar Sithara, Lucie Hofmanová, David ŽIHALA, Dhwani Radhakrishnan, Alexander Vdovin, Sofija Knápková, Tereza Ševčíková, Zuzana Chyra, Tomáš Jelínek, Michal Šimíček, Annamaria Gulla, Kenneth Carl Anderson, Roman Hájek, Matouš Hrdinka ... other authors

Year: 2023, International Journal of Molecular Sciences

journal article

Circulating Tumor and Immune Cells for Minimally Invasive Risk Stratification of Smoldering Multiple Myeloma

Rosalinda Termini, David ŽIHALA, Evangelos Terpos, Albert Perez-Montana, Tomáš Jelínek, Marc Raab, Niels Weinhold, Elias K. Mai, Anna Luise Grab, Jill Corre, Francois Vergez, Antonio Sacco, Marco Chiarini, Viviana Giustini, Alessandra Tucci, Sara Rodriguez, Cristina Moreno, Cristina Perez, Catarina Maia, Esperanza Martin-Sanchez, Camilla Guerrero, Cirino Botta, Juan-Jose Garces, Aitziber Lopez, Luis-Esteban Tamariz-Amador, Felipe Prosper, Joan Bargay, Maria-Elena Cabezudo, Enrique M. Ocio, Roman Hájek, Joaquin Martinez-Lopez, Fernando Solano, Rebeca Iglesias, Artur Paiva, Catarina Geraldes, Helena Vitoria, Clara Gomez, Felipe De Arriba, Heinz Ludwig, Antoni Garcia-Guinon, Maria Casanova, Adrian Alegre, Valentin Cabanas, Maialen Sirvent, Albert Oriol, Javier de la Rubia, Jose-Angel Hernandez-Rivas, Luis Palomera, Maria Sarasa, Pablo Rios, Noemi Puig, Maria-Victoria Mateos, Juan Flores-Montero, Alberto Orfao, Hartmut Goldschmidt, Herve Avet-Loiseau, Aldo M. Roccaro, Jesus F. San-Miguel, Bruno Paiva ... other authors

Year: 2022, Clinical Cancer Research

journal article

Deubiquitinase OTUD1 Resolves Stalled Translation on polyA and Rare Codon Rich mRNAs

Renáta Šnaurová, Alexander Vdovin, Michal Ďurech, Jakub Nezval, David ŽIHALA, Tomáš Jelínek, Roman Hájek, Michal Šimíček ... other authors

Year: 2022, Molecular and Cellular Biology

journal article

Evidence for an independent hydrogenosome-to-mitosome transition in the CL3 lineage of fornicates

Romana Vargová, Pavla Hanouskova, Jana Salamonová, David ŽIHALA, Jeffrey D. Silberman, Marek Eliáš, Ivan Cepicka ... other authors

Year: 2022, Frontiers in Microbiology

journal article

Limited efficacy of daratumumab in multiple myeloma with extramedullary disease

Tomáš Jelínek, Tereza Ševčíková, David ŽIHALA, Tereza Popková, Veronika Kapustová, Lucie Broskevičová, Lenka Capkova, Lucie Rihova, Renata Bezdekova, Sabina Sevcikova, Vladimir Zidlik, Martin Havel, Hana Plonkova, Alexandra Jungova, Jiri Minarik, Martin Stork, Ludek Pour, Petr Pavlicek, Ivan Spicka, Vladimir Maisnar, Jakub Radocha, Michal Šimíček, Roman Hájek ... other authors

Year: 2022, Leukemia

journal article

Mutation landscape of multiple myeloma measurable residual disease: identification of targets for precision medicine

Martina Zátopková, Tereza Ševčíková, Viola Fanfani, Zuzana Chyra, Lucie Rihova, Renata Bezdekova, David ŽIHALA, Kateřina Growková, Jana Filipová, Lucie Černá, Lucie Broskevicova, Fedor Kryukov, Jiri Minarik, Jana Smejkalova, Vladimir Maisnar, Lubica Harvanova, Ludek Pour, Alexandra Jungova, Tereza Popková, Julio Rodriguez Bago, Anjana Anilkumar Sithara, Matouš Hrdinka, Tomáš Jelínek, Michal Šimíček, Giovanni Stracquadanio, Roman Hájek ... other authors

Year: 2022, Blood Advances

journal article

The deubiquitinase OTUD1 regulates immunoglobulin production and proteasome inhibitor sensitivity in multiple myeloma

Alexander Vdovin, Tomáš Jelínek, David ŽIHALA, Tereza Ševčíková, Michal Ďurech, Hana Šahinbegović, Renáta Šnaurová, Dhwani Radhakrishnan, Marcello Turi, Zuzana Chyra, Tereza Popková, Ondřej Venglář, Matouš Hrdinka, Roman Hájek, Michal Šimíček ... other authors

Year: 2022, Nature Communications

journal article

PhyloFisher: A phylogenomic package for resolving eukaryotic relationships

Alexander K. Tice, David ŽIHALA, Tomáš Pánek, Robert E. Jones, Eric D. Salomaki, Serafim Nenarokov, Fabien Burki, Marek Eliáš, Laura Eme, Andrew J. Roger, Antonis Rokas, Xing-Xing Shen, Jurgen F. H. Strassert, Martin Kolísko, Matthew W. Brown ... other authors

Year: 2021, PLOS BIOL

journal article

Evolution of the genetic code in the mitochondria of Labyrinthulea (Stramenopiles)

David ŽIHALA, Jana Salamonová, Marek Eliáš

Year: 2020, MOL PHYLOGENET EVOL

journal article

Genomics of New Ciliate Lineages Provides Insight into the Evolution of Obligate Anaerobiosis

J Rotterova, E Salomaki, T Panek, W Bourland, David ŽIHALA, P Taborsky, VP Edgcomb, RA Beinart, M Kolisko, I Cepicka ... other authors

Year: 2020, CURR BIOL

journal article

Comparative genomics of Leishmania (Mundinia)

Anzhelika Butenko, Aleksei Kostygov, J. Sádlová, Y. Kleschenko, T. Bečvář, Lucie Podešvová, Diego Henrique Macedo, David ŽIHALA, J. Lukeš, P. A. Bates, P. Volf, F. R. Opperdoes, Vyacheslav Yurchenko ... other authors

Year: 2019, BMC Genomics

journal article

Evolution and Unprecedented Variants of the Mitochondria! Genetic Code in a Lineage of Green Algae

David ŽIHALA, Marek Eliáš

Year: 2019, Genome Biology and Evolution

journal article

The oxymonad genome displays canonical eukaryotic complexity in the absence of a mitochondrion

A. Karnkowska, S. C. Treitli, O. Brzoň, L. Novák, V. Vacek, P. Soukal, L. D. Barlow, E. K. Herman, S. V. Pipaliya, Tomáš Pánek, David ŽIHALA, Romana Petrželková, Anzhelika Butenko, L. Eme, C. W. Stairs, A. J. Roger, Marek Eliáš, J. B. Dacks, V. Hampl ... other authors

Year: 2019, Molecular Biology and Evolution

journal article

Nuclear genetic codes with a different meaning of the UAG and the UAA codon

Tomáš Pánek, David ŽIHALA, Martin Sokol, R. Derelle, Vladimír Klimeš, M. Hradilova, E. Zadrobilkova, E. Susko, A.J. Roger, I. Cepicka, Marek Eliáš ... other authors

Year: 2017, BMC BIOLOGY

journal article

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Abbreviation

Subject

7BINF

Bioinformatika